Krupp S, Torhorst J
Helv Chir Acta. 1978 Jan;44(5-6):639-45.
The indication for subcutaneous mastectomy is analyzed. Prospective investigations seem to confirm that different morphological forms of breast dysplasia (grade I, II, III, PRECHTEL [10]) do not implicate differences in risk for development of invasive breast cancer. Only if these forms of breast dysplasia are associated to high risk factors such as family history of breast cancer, should subcutaneous mastectomy be considered as a cancer prophylaxis.
分析了皮下乳房切除术的适应症。前瞻性研究似乎证实,不同形态学类型的乳腺发育异常(I级、II级、III级,PRECHTEL [10])与浸润性乳腺癌发生风险的差异无关。只有当这些乳腺发育异常形式与乳腺癌家族史等高危因素相关时,才应考虑将皮下乳房切除术作为一种癌症预防措施。