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[乳腺癌癌前病变及非浸润性癌的手术策略]

[Surgical tactics in precancerous conditions and non-invasive cancers of the breast].

作者信息

Herfarth C, Schlag P

出版信息

Chirurg. 1982 Jan;53(1):29-33.

PMID:6277574
Abstract

In the treatment of non-palpable lesions of the breast, geometric localization technique with subcutaneous segmental mastectomy and intraoperative specimen radiography proved to be safe. Permanent sectioning of the whole excised area is recommended to improve the reliability of diagnosis. If breast biopsy establishes proliferative mastopathy with cell atypia or papillary proliferation, a strict clinical follow-up of the patient is adequate. When lobular neoplasia is detected, both breasts are in danger of developing carcinoma. In the treatment of this lesion, the calculated risk of life-long follow-ups may sometimes be an acceptable alternative to the certain cure by (subcutaneous) mastectomy. Yet, for treatment purposes intraductal carcinoma, with its risk of occult infiltration, should be considered potentially invasive.

摘要

在乳腺不可触及病变的治疗中,皮下节段性乳房切除术联合术中标本放射摄影的几何定位技术被证明是安全的。建议对整个切除区域进行永久切片以提高诊断的可靠性。如果乳腺活检确诊为伴有细胞异型性或乳头状增生的增生性乳腺病,对患者进行严格的临床随访即可。当检测到小叶肿瘤时,双侧乳房均有发生癌变的风险。在治疗这种病变时,终身随访所计算出的风险有时可能是(皮下)乳房切除术确定性治愈之外的可接受替代方案。然而,出于治疗目的,导管内癌因其存在隐匿浸润的风险,应被视为具有潜在侵袭性。

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