Bürgi H
Helv Chir Acta. 1978 Jan;44(5-6):709-18.
A review of the literature shows that thyroid hormone therapy causes 13 to 40% of euthyroid goiters to disappear and brings about a reduction in goiter size in another 30 to 50%. The hormonal treatment is more successful with smaller goiters. Uninodular goiters respond on the average less well than diffuse and multinodular goiters. In Switzerland, about 33% of adult persons have goiters, albeit mostly of small size. This renders impracticable investigation or treatment of all goiters. It is recommended that only goiters which are esthetically disturbing or which cause pressure symptoms be treated. An operation must always be performed when there is suspicion of thyroid cancer or in the presence of threatening pressure symptoms. In all the other cases, thyroid hormone therapy may be tried. If an operation cannot be performed for cardiac or other reasons, radioiodine will relieve pressure symptoms due to goiter in over 65% of cases.
文献综述表明，甲状腺激素疗法可使13%至40%的甲状腺功能正常的甲状腺肿消失，并使另外30%至50%的甲状腺肿缩小。激素治疗对较小的甲状腺肿更有效。单结节性甲状腺肿的平均反应不如弥漫性和多结节性甲状腺肿。在瑞士，约33%的成年人患有甲状腺肿，尽管大多为小尺寸。这使得对所有甲状腺肿进行检查或治疗变得不切实际。建议仅对那些在美观上造成困扰或引起压迫症状的甲状腺肿进行治疗。当怀疑有甲状腺癌或存在威胁性压迫症状时，必须始终进行手术。在所有其他情况下，可以尝试甲状腺激素疗法。如果由于心脏或其他原因无法进行手术，放射性碘在超过65%的病例中可缓解甲状腺肿引起的压迫症状。
