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用阿糖腺苷治疗疱疹性脑炎并进行光密度测定随访(作者译)

[Herpes encephalitis treated using adenine-arabino-side and followed-up by densitometry (author's transl)].

作者信息

Roux F X, Thurel C, Evrard E

出版信息

Nouv Presse Med. 1980 Mar 1;9(10):693-5.

PMID:6246478
Abstract

In a 52-year-old man suffering from encephalitis, immunofluorescent study of cerebral tissue led to a diagnosis of herpes encephalitis 4 hours after biopsy. Cell cultures on the fourth day confirmed the diagnosis. Such a hypothesis had already been advanced before biopsy on the basis of the electroencephalogram which showed electrical changes with a periodic tendency. Following treatment with adenine-arabinoside, motor deficit and aphasia disappeared in one month whilst there was a parallel increase in antibody levels in the blood and cerebrospinal fluid.

摘要

在一名52岁的脑炎男性患者中,对脑组织进行免疫荧光研究,活检后4小时诊断为疱疹性脑炎。第四天的细胞培养证实了诊断。在活检前,基于脑电图显示出具有周期性倾向的电变化,就已经提出了这样的假设。在用阿糖腺苷治疗后,运动功能障碍和失语症在一个月内消失,同时血液和脑脊液中的抗体水平相应升高。

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