Del Vecchio P J, Ryan J W, Chung A, Ryan U S
Biochem J. 1980 Feb 15;186(2):605-8. doi: 10.1042/bj1860605.
The enzymes required to convert the prohormone angiotensin I into angiotensins II and III, secretagogues of aldosterone, are enriched in association with capillary endothelium isolated from rat adrenal cortex. Thus the secretion of aldosterone may be controlled, in part, by processing of peptides occurring within the adrenal gland itself.
将前体激素血管紧张素I转化为血管紧张素II和III(醛固酮的促分泌素)所需的酶,在从大鼠肾上腺皮质分离出的毛细血管内皮中大量存在。因此,醛固酮的分泌可能部分受肾上腺自身内肽加工过程的控制。