Oppenheimer D R
J Neurol Sci. 1980 Jun;46(3):393-404. doi: 10.1016/0022-510x(80)90064-7.
Estimates of cell loss in the intermediolateral columns of the thoracic cord in cases of progressive autonomic failure were made by counting nerve cells in the lateral grey horns from 21 such cases, and comparing (a) with "normal" controls, (b) with 3 cases of uncomplicated Parkinson's disease and (c) with 3 cases of multiple system atrophy without overt autonomic failure. It was found that all cases of autonomic failure had suffered severe cell loss; on average three quarters of their lateral horn cells were lost. The cases of uncomplicated Parkinson's disease did not differ from the controls; but the cases of multiple system atrophy without autonomic disturbances had lost about half their lateral horn cells. These findings are tabulated, and discussed.
通过对21例进行性自主神经功能衰竭患者胸段脊髓中间外侧柱的细胞丢失情况进行评估，方法是对这些患者的外侧灰质角中的神经细胞进行计数，并与（a）“正常”对照组、（b）3例单纯帕金森病患者以及（c）3例无明显自主神经功能衰竭的多系统萎缩患者进行比较。结果发现，所有自主神经功能衰竭患者均出现严重的细胞丢失；平均而言，其外侧角细胞丢失了四分之三。单纯帕金森病患者与对照组无差异；但无自主神经功能障碍的多系统萎缩患者外侧角细胞丢失了约一半。这些结果已列表并进行了讨论。
