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运动神经元病和夏伊-德雷格综合征中间外侧柱细胞的定量研究。

A quantitative study of intermediolateral column cells in motor neuron disease and the Shy-Drager syndrome.

作者信息

Kennedy P G, Duchen L W

出版信息

J Neurol Neurosurg Psychiatry. 1985 Nov;48(11):1103-6. doi: 10.1136/jnnp.48.11.1103.

DOI:10.1136/jnnp.48.11.1103
PMID:4078575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1028568/
Abstract

The intermediolateral column neurons in the lateral horns of the grey matter of the thoracic spinal cord were counted in five patients who had died of motor neuron disease, two of the Shy-Drager syndrome and three of other neurological diseases not affecting the spinal cord or roots. The number of intermediolateral column cells in all the motor neuron disease cases was slightly reduced compared with the control cords, this difference being apparent both when the whole thoracic sympathetic outflow was assessed as well as its upper, middle and lower thirds. The difference, however, was not statistically significant. By contrast, in Shy-Drager cases there was a highly significant reduction in intermediolateral column cells compared with the normal cords.

摘要

对5例死于运动神经元病的患者、2例死于夏伊-德雷格综合征的患者以及3例死于不影响脊髓或神经根的其他神经系统疾病的患者,计数其胸段脊髓灰质侧角中间外侧柱神经元。与对照脊髓相比,所有运动神经元病病例的中间外侧柱细胞数量均略有减少,无论是评估整个胸段交感神经传出纤维,还是其上、中、下三分之一部分时,这种差异均很明显。然而,这种差异无统计学意义。相比之下,与正常脊髓相比,夏伊-德雷格综合征病例的中间外侧柱细胞有极显著减少。

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