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Pharmacological evidence for a functional role of the prejunctional alpha-adrenoreceptor in noradrenergic neurotransmission in the conscious rat.

作者信息

Graham R M, Stephenson W H, Pettinger W A

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1980 Mar;311(2):129-38. doi: 10.1007/BF00510251.

DOI:10.1007/BF00510251
PMID:6247660
Abstract
摘要

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1
Pharmacological evidence for a functional role of the prejunctional alpha-adrenoreceptor in noradrenergic neurotransmission in the conscious rat.关于突触前α-肾上腺素能受体在清醒大鼠去甲肾上腺素能神经传递中的功能作用的药理学证据。
Naunyn Schmiedebergs Arch Pharmacol. 1980 Mar;311(2):129-38. doi: 10.1007/BF00510251.
2
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Clin Exp Hypertens (1978). 1980 Feb;2(2):273-96. doi: 10.3109/10641968009046424.
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Role of prejunctional alpha 2-adrenergic receptors in the regulation of myocardial performance during exercise in conscious dogs.接头前α2-肾上腺素能受体在清醒犬运动期间心肌功能调节中的作用。
Circ Res. 1984 Jun;54(6):683-93. doi: 10.1161/01.res.54.6.683.
4
Reduction in norepinephrine content of sympathetic neuroeffector organs by alpha adrenergic antagonists and nerve stimulation: evidence for presynaptic control of sympathetic transmitter release in intact animal.
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5
Effects of prazosin and phentolamine on arterial pressure, heart rate, and renin activity: evidence in the conscious rat for the functional significance of the presynaptic alpha-receptor.
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6
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Br J Pharmacol. 1982 Jun;76(2):235-43. doi: 10.1111/j.1476-5381.1982.tb09212.x.
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Effects of tiodazosin, praxosin, trimazosin and phentolamine on blood pressure, heart rate and on pre- and postsynaptic alpha-adrenergic receptors in the rat.哌唑嗪、普拉唑嗪、曲马唑嗪和酚妥拉明对大鼠血压、心率及突触前和突触后α-肾上腺素能受体的影响。
Clin Exp Hypertens (1978). 1980;2(6):1039-66. doi: 10.3109/10641968009037160.
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Evidence against presynaptic alpha-adrenoreceptor modulation of cardiac sympathetic transmission.反对心脏交感神经传递中突触前α-肾上腺素能受体调节的证据。
Nature. 1980 Jul 17;286(5770):288-91. doi: 10.1038/286288a0.
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Complete blockade by phenoxybenzamine of alpha 1- but not of alpha 2-vascular receptors in dogs and the effects of propranolol.苯氧苄胺对犬α1而非α2血管受体的完全阻断作用及普萘洛尔的影响。
Naunyn Schmiedebergs Arch Pharmacol. 1980 Nov;314(2):149-56. doi: 10.1007/BF00504531.

引用本文的文献

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The role of presynaptic alpha-adrenoceptors in the regulation of blood pressure in the conscious rabbit.突触前α-肾上腺素能受体在清醒兔血压调节中的作用。
Br J Pharmacol. 1982 Mar;75(3):417-24. doi: 10.1111/j.1476-5381.1982.tb09156.x.
2
Differential blockade of alpha-adrenoceptors by indoramin.吲哚拉明对α-肾上腺素能受体的选择性阻断作用
Br J Clin Pharmacol. 1984 Jun;17(6):719-28. doi: 10.1111/j.1365-2125.1984.tb02409.x.
3
Evidence for a physiological role of presynaptic alpha-adrenoceptors: modulation of noradrenaline release in the pithed rabbit.

本文引用的文献

1
Routine direct measurement of arterial pressure in unanesthetized rats.未麻醉大鼠动脉压的常规直接测量。
Proc Soc Exp Biol Med. 1960 Aug-Sep;104:646-8. doi: 10.3181/00379727-104-25937.
2
Studies on hydralazine; evidence for a peripheral site of action.关于肼屈嗪的研究；作用于外周部位的证据。
J Clin Invest. 1954 Jul;33(7):1047-53. doi: 10.1172/JCI102972.
3
Pharmacological evidence for stimulation of growth hormone secretion by a central noradrenergic system in dogs.犬中枢去甲肾上腺素能系统刺激生长激素分泌的药理学证据。
突触前α-肾上腺素能受体生理作用的证据：在去大脑兔中对去甲肾上腺素释放的调节
Naunyn Schmiedebergs Arch Pharmacol. 1983 Dec;324(4):256-63. doi: 10.1007/BF00502620.
4
The effects of yohimbine on presynaptic and postsynaptic events during sympathetic nerve activation in cattle iris: a critique of presynaptic receptor theory.育亨宾对牛虹膜交感神经激活过程中突触前和突触后事件的影响：对突触前受体理论的批判
Br J Pharmacol. 1983 Jan;78(1):247-53. doi: 10.1111/j.1476-5381.1983.tb09386.x.
5
The pharmacokinetic properties of yohimbine in the conscious rat.育亨宾在清醒大鼠体内的药代动力学特性。
Naunyn Schmiedebergs Arch Pharmacol. 1988 May;337(5):583-7. doi: 10.1007/BF00182736.
6
The measurement of norepinephrine clearance and spillover rate into plasma in conscious spontaneously hypertensive rats.清醒自发性高血压大鼠去甲肾上腺素清除率及向血浆溢出率的测定。
Naunyn Schmiedebergs Arch Pharmacol. 1988 Oct;338(4):350-60. doi: 10.1007/BF00172109.
7
The physiological and pharmacological role of presynaptic alpha- and beta-adrenoceptors in man.人类突触前α和β肾上腺素能受体的生理及药理作用
Br J Clin Pharmacol. 1985 Dec;20(6):649-58. doi: 10.1111/j.1365-2125.1985.tb05124.x.
8
Is the sympathoexcitatory effect of yohimbine determined by brain yohimbine concentration?
Naunyn Schmiedebergs Arch Pharmacol. 1991 Sep;344(3):308-13. doi: 10.1007/BF00183005.
9
Macro- and microvascular effects of nitrous oxide in the rat.一氧化二氮对大鼠的大血管和微血管作用
Anesth Prog. 1991 Mar-Apr;38(2):57-64.
Neuroscience. 1976 Dec;1(6):443-50. doi: 10.1016/0306-4522(76)90094-4.
4
Studies of the effect of phenoxybenzamine on the uptake of noradrenaline and on the response to sympathetic stimulation of rat hearts.苯氧苄胺对大鼠心脏去甲肾上腺素摄取及交感神经刺激反应影响的研究。
Arch Int Pharmacodyn Ther. 1973 Feb;201(2):400-14.
5
Presynaptic regulation of catecholamine release.儿茶酚胺释放的突触前调节。
Biochem Pharmacol. 1974 Jul 1;23(13):1793-800. doi: 10.1016/0006-2952(74)90187-7.
6
Interactions between 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride (St 155, Catapresan) and alpha-adrenergic blocking drugs.
Eur J Pharmacol. 1970 Jan;9(1):7-13. doi: 10.1016/0014-2999(70)90313-4.
7
Catecholamine uptake processes.儿茶酚胺摄取过程
Br Med Bull. 1973 May;29(2):130-5. doi: 10.1093/oxfordjournals.bmb.a070982.
8
A simplified radiometric assay for plasma norepinephrine and epinephrine.一种用于检测血浆去甲肾上腺素和肾上腺素的简化放射测定法。
Anal Biochem. 1973 Feb;51(2):618-31. doi: 10.1016/0003-2697(73)90517-4.
9
Role of the -adrenoceptor in regulating noradrenaline overflow by nerve stimulation.β-肾上腺素能受体在通过神经刺激调节去甲肾上腺素溢出中的作用。
Br J Pharmacol. 1972 Apr;44(4):672-88. doi: 10.1111/j.1476-5381.1972.tb07306.x.
10
Local alpha-adrenoceptor mediated feed-back inhibition of catecholamine release from the adrenal medulla?局部α-肾上腺素能受体介导的对肾上腺髓质儿茶酚胺释放的反馈抑制？
Experientia. 1974 Oct 15;30(10):1170-2. doi: 10.1007/BF01923671.