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[感染A型产气荚膜梭菌毒素以及毒素与肉汤培养滤液混合物的豚鼠血清酸性磷酸酶活性变化]

[Changes in the serum acid phosphatase activity of guinea pigs poisoned with C1 perfringens type A toxin and a mixture of toxin and a broth culture filtrate].

作者信息

Tselukh A V, Levitskiĭ A P, Shtefan E E

出版信息

Biull Eksp Biol Med. 1980 Apr;89(4):426-8.

PMID:6248148
Abstract

It was shown in experiments on guinea pigs that the injection of C1. perfringens type A toxoid induced an increase in acid phosphatase activity of animal blood serum. The action of the toxoid increased under the effect of C1. butyricum cultural filtrate, which gave rise to an earlier enhancement of the specific activity of the enzyme as compared to the injection of the toxoid alone. Increased activity of acid phosphatase may play a pathogenetic role in cases of anaerobic infection caused by association of C1. perfringens and C1. butyricum.

摘要

在豚鼠实验中表明,注射A型产气荚膜梭菌类毒素会导致动物血清酸性磷酸酶活性增加。在丁酸梭菌培养滤液的作用下,类毒素的作用增强,与单独注射类毒素相比,这导致酶的比活性更早增强。酸性磷酸酶活性增加可能在由产气荚膜梭菌和丁酸梭菌联合引起的厌氧感染病例中发挥致病作用。

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