[Effect of aminazin on changes in the electrical activity of the cerebral cortex under the influence of the toxin C1. perfringens type A].

Experiments on cats revealed that injection of chlorpromazine (3 mg/kg of body weight, intramuscular) one hour prior to the Cl. perfingens toxin type A injection prevented the appearance of desynchronization of the electrical activity of the cerebral cortex usually observed during the first phase of intoxication. Chlorpromazine injection postpones the appearance of the electrical activity depression phase during the second phase and prolonged the animals' life span from 1.5 to 2 times. The effect of chlorpromazine was apparently connected with the block of the adrenergic structures of the brain stem reticular formation.