Rosenberg E M, Lee S W, Chase L R, Avioli L V
J Lab Clin Med. 1980 Jul;96(1):24-35.
The effects of metabolic and transport inhibitors and PTH, cAMP, db-cAMP, and theophylline on Pi uptake by an isolated rat renal tubular preparation has been investigated. Pi uptake by this preparation was a saturable process, was O2- and sodium-dependent, was inactivated by heat=treatment, and was inhibited by dinitrophenol. iodacetate, ouabain, and a decrease in temperature from 37 degrees to 4 degrees C. PTH and cAMP stimulated Pi uptake by energy-dependent and ouabain-inhibitable mechanisms.
研究了代谢和转运抑制剂以及甲状旁腺激素（PTH）、环磷酸腺苷（cAMP）、双丁酰环磷腺苷（db - cAMP）和茶碱对离体大鼠肾小管制剂摄取无机磷（Pi）的影响。该制剂对Pi的摄取是一个可饱和的过程，依赖于氧气和钠，经热处理会失活，并受到二硝基苯酚、碘乙酸盐、哇巴因的抑制，以及温度从37摄氏度降至4摄氏度的抑制。PTH和cAMP通过能量依赖且可被哇巴因抑制的机制刺激Pi摄取。
