• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Opioid binding properties of brain and peripheral tissues: evidence for heterogeneity in opioid ligand binding sites.

作者信息

Leslie F M, Chavkin C, Cox B M

出版信息

J Pharmacol Exp Ther. 1980 Aug;214(2):395-402.

PMID:6248635
Abstract
摘要

相似文献

1
Opioid binding properties of brain and peripheral tissues: evidence for heterogeneity in opioid ligand binding sites.脑和外周组织的阿片样物质结合特性：阿片样物质配体结合位点存在异质性的证据。
J Pharmacol Exp Ther. 1980 Aug;214(2):395-402.
2
Characteristics of peptide and alkaloid opiate binding sites in brain and peripheral tissues.脑和外周组织中肽和生物碱阿片样物质结合位点的特征
Adv Biochem Psychopharmacol. 1980;22:353-62.
3
Some aspects of opiate receptors.
Adv Biochem Psychopharmacol. 1980;21:329-37.
4
Synthesis, opioid receptor binding, and biological activities of naltrexone-derived pyrido- and pyrimidomorphinans.纳曲酮衍生的吡啶并和嘧啶并吗啡喃的合成、阿片受体结合及生物活性
J Med Chem. 1999 Sep 9;42(18):3527-38. doi: 10.1021/jm990039i.
5
Biosynthesis of the enkephalins in the myenteric plexus of the guinea pig ileum: further analysis of the interaction of the enkephalins and their analogues with the opiate receptors.豚鼠回肠肌间神经丛中脑啡肽的生物合成：脑啡肽及其类似物与阿片受体相互作用的进一步分析。
NIDA Res Monogr. 1979;27:48-53.
6
Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and related novel nonpeptide delta opioid receptor ligands.用于麻醉受体介导现象的探针。23. 高选择性δ激动剂(+)-4-[(αR)-α-((2S,5R)-4-烯丙基-2,5-二甲基-1-哌嗪基)-3-甲氧基苄基]-N,N-二乙基苯甲酰胺(SNC 80)及相关新型非肽类δ阿片受体配体的合成、阿片受体结合及生物测定
J Med Chem. 1997 Feb 28;40(5):695-704. doi: 10.1021/jm960319n.
7
The preference of putative pro-enkephalins for different types of opiate receptors.
Life Sci. 1981 Sep 21;29(12):1219-27. doi: 10.1016/0024-3205(81)90226-5.
8
Guanyl nucleotide interactions with opiate receptors in guinea pig brain and ileum.鸟苷酸与豚鼠脑和回肠中阿片受体的相互作用。
Brain Res. 1980 Mar 31;186(2):486-91. doi: 10.1016/0006-8993(80)90996-8.
9
Biochemical characterization of high-affinity 3H-opioid binding. Further evidence for Mu1 sites.高亲和力3H-阿片样物质结合的生化特性。对Mu1位点的进一步证据。
Mol Pharmacol. 1984 Jan;25(1):29-37.
10
Comparison of binding of [3H]-methionine-enkephalin, [3H]-naltrexone and [3H]-dihydromorphine in the mouse vas deferens and the myenteric plexus and brain of the ginea pig.[3H]-蛋氨酸脑啡肽、[3H]-纳曲酮和[3H]-二氢吗啡在小鼠输精管、豚鼠肠肌丛和脑中的结合比较。
Eur J Pharmacol. 1979 Jul 1;56(4):379-83. doi: 10.1016/0014-2999(79)90269-3.

引用本文的文献

1
The OGF-OGFr axis utilizes the p16INK4a and p21WAF1/CIP1 pathways to restrict normal cell proliferation.OGF-OGFr轴利用p16INK4a和p21WAF1/CIP1途径来限制正常细胞增殖。
Mol Biol Cell. 2009 Jan;20(1):319-27. doi: 10.1091/mbc.e08-07-0681. Epub 2008 Oct 15.
2
Activity of mu- and delta-opioid agonists in vas deferens from mice deficient in MOR gene.μ-和δ-阿片样物质激动剂在MOR基因缺陷小鼠输精管中的活性。
Br J Pharmacol. 2001 Apr;132(7):1485-92. doi: 10.1038/sj.bjp.0703966.
3
Evidence for lack of modulation of mu-opioid agonist action by delta-opioid agonists in the mouse vas deferens and guinea-pig ileum.
在小鼠输精管和豚鼠回肠中缺乏δ-阿片样激动剂对μ-阿片样激动剂作用调节的证据。
Br J Pharmacol. 1995 Mar;114(5):1064-8. doi: 10.1111/j.1476-5381.1995.tb13314.x.
4
Differential effects of SKF 10,047 (N-allyl-normetazocine) on peristalsis and longitudinal muscle contractions of the isolated guinea-pig ileum.SKF 10,047（N-烯丙基去甲左啡诺）对离体豚鼠回肠蠕动和纵肌收缩的不同作用。
Naunyn Schmiedebergs Arch Pharmacol. 1982 Dec;321(3):218-22. doi: 10.1007/BF00505489.
5
Reduction by phentolamine of the hypotensive effect of methionine enkephalin in anaesthetized rabbits.酚妥拉明对麻醉兔中甲硫氨酸脑啡肽降压作用的减弱
Br J Pharmacol. 1984 Nov;83(3):783-90. doi: 10.1111/j.1476-5381.1984.tb16233.x.
6
Effects of opioids on noncholinergic excitatory responses of the guinea-pig isolated ileum: inhibition of release of enteric substance P.阿片类药物对豚鼠离体回肠非胆碱能兴奋性反应的影响：抑制肠P物质的释放
Br J Pharmacol. 1982 Jan;75(1):199-205. doi: 10.1111/j.1476-5381.1982.tb08773.x.
7
Opiates induce long-term increases in prodynorphin-derived peptide levels in the guinea-pig myenteric plexus.阿片类药物可使豚鼠肠肌间神经丛中源自前强啡肽的肽水平长期升高。
Naunyn Schmiedebergs Arch Pharmacol. 1986 Aug;333(4):381-6. doi: 10.1007/BF00500013.
8
Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid receptors in rat brain.大鼠脑中中性内肽酶“脑啡肽酶”以及μ和δ阿片受体分布的放射自显影比较
Proc Natl Acad Sci U S A. 1986 Mar;83(5):1523-7. doi: 10.1073/pnas.83.5.1523.
9
Determination of the receptor selectivity of opioid agonists in the guinea-pig ileum and mouse vas deferens by use of beta-funaltrexamine.使用β-芬太尼环唑来测定豚鼠回肠和小鼠输精管中阿片类激动剂的受体选择性。
Br J Pharmacol. 1985 Dec;86(4):899-904. doi: 10.1111/j.1476-5381.1985.tb11112.x.
10
Characterization of rat brain opioid receptors by [Tyr-3,5-3H]1, D-Ala2, Leu5-enkephalin binding.
Neurochem Res. 1985 May;10(5):627-35. doi: 10.1007/BF00964402.