Wyeth P J
Vet Rec. 1980 Mar 29;106(13):289-90. doi: 10.1136/vr.106.13.289.
Vaccination of broiler breeder parents with live infectious bursal disease (IBD) vaccine by the oral route resulted in higher and more persistent quantitative gel diffusion precipitins than vaccination by intramuscular injection. All the progeny of the orally vaccinated parents had maternally derived IBD antibody (MDA) at hatching while MDA was detected in only 35 per cent of the progeny of the intramuscularly vaccinated parents. This MDA had disappeared completely at 14 and eight days respectively. Susceptibility to IBD challenge began at eight days in the first group and at one day old in the second. The age of 100 per cent susceptibility occurred at 19 and 11 days in the respective groups.
通过口服途径用传染性法氏囊病（IBD）活疫苗对肉种鸡亲本进行免疫接种，所产生的定量凝胶扩散沉淀素比肌肉注射接种更高且更持久。口服免疫接种亲本的所有后代在孵化时都有母源IBD抗体（MDA），而肌肉注射接种亲本的后代中只有35%检测到MDA。这种MDA分别在14天和8天时完全消失。第一组在8日龄开始对IBD攻毒敏感，第二组在1日龄开始敏感。两组分别在19日龄和11日龄时达到100%的易感性。
