• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

高血压、血管系统与衰老。

Hypertension, vasculature and aging.

作者信息

Ooshima A, Yamori Y

出版信息

Adv Exp Med Biol. 1980;129:99-110. doi: 10.1007/978-1-4684-3734-8_10.

DOI:10.1007/978-1-4684-3734-8_10
PMID:6249098
Abstract

Essential hypertension is the most common disease which develops with advancing age, and its complication, arteriosclerosis, seems to be an exaggerated form of aging process in the mesenchymal tissues. Our present investigation demonstrated that deposition of collagen fibers in vessel wall may represent one aspect of the aging phenomenon occurring in normal vasculature.

摘要

原发性高血压是随着年龄增长而出现的最常见疾病,其并发症动脉硬化似乎是间充质组织衰老过程的一种过度形式。我们目前的研究表明,血管壁中胶原纤维的沉积可能代表了正常血管系统中发生的衰老现象的一个方面。

相似文献

1
Hypertension, vasculature and aging.高血压、血管系统与衰老。
Adv Exp Med Biol. 1980;129:99-110. doi: 10.1007/978-1-4684-3734-8_10.
2
Effect of guanethidine on collagen biosynthesis in blood vessels of hypertensive rats.胍乙啶对高血压大鼠血管中胶原生物合成的影响。
Arch Int Pharmacodyn Ther. 1979 Aug;240(2):278-84.
3
Collagen biosynthesis in blood vessels of brain and other tissues of the hypertensive rat.
Science. 1975 Nov 28;190(4217):898-900. doi: 10.1126/science.171771.
4
Increased collagen synthesis in blood vessels of hypertensive rats and its reversal by antihypertensive agents.高血压大鼠血管中胶原蛋白合成增加及其被抗高血压药物逆转。
Proc Natl Acad Sci U S A. 1974 Aug;71(8):3019-23. doi: 10.1073/pnas.71.8.3019.
5
Age-related changes in the vascular collagen metabolism of the spontaneously hypertensive rat.
Exp Gerontol. 1978;13(1-2):83-9. doi: 10.1016/0531-5565(78)90034-7.
6
Changes in glomerular basement membrane collagen caused by DOCA-NaCl treatment in rats.
Nephron. 1985;39(3):250-4. doi: 10.1159/000183380.
7
Influence of age and treatment with sodium chloride and desoxycorticosterone acetate on collagenous stroma of compensatory growing kidneys in the rat.年龄以及氯化钠和醋酸去氧皮质酮处理对大鼠代偿性生长肾脏胶原基质的影响。
Mech Ageing Dev. 1974 Jul-Aug;3(2):157-63. doi: 10.1016/0047-6374(74)90012-8.
8
Effects of prolyl hydroxylase inhibition on arterial collagen synthesis and blood pressure in hypertensive rats.
Pharmacology. 1984;29(5):255-63. doi: 10.1159/000138021.
9
Reduction of blood pressure and vascular collagen in the spontaneously hypertensive rat by elastase.
Arch Int Pharmacodyn Ther. 1983 May;263(1):63-73.
10
Nonsynchronous changes in myocardial collagen mRNA and protein during aging: effect of DOCA-salt hypertension.
Am J Physiol. 1994 Dec;267(6 Pt 2):H2237-44. doi: 10.1152/ajpheart.1994.267.6.H2237.