猪输卵管细胞系在仓鼠体内诱发肿瘤
Production of tumors in hamsters by cells of a pig uterine tube line.
作者信息
Bouillant A M, Bundza A, Genest P, Greig A S
出版信息
Can J Comp Med. 1980 Jan;44(1):77-86.
Abstract
Tumorigenicity was investigated in a pig established cell line continuously subcultured more than 400 times. Tumors were not found in hamsters' cheek pouches inoculated with cells from the first 200 subcultures. Fibroma developed in five out of 13 animals (9/26 pouches) inoculated with cells of the 313th and 314th subcultures. Two chromosome markers were found in the 290th subculture, in the 313th subculture inoculum and in tumor cells.
摘要
在一个连续传代超过400次的猪源细胞系中研究致瘤性。在前200代细胞接种到仓鼠颊囊后未发现肿瘤。用第313和314代细胞接种的13只动物中有5只（26个颊囊中9个）发生了纤维瘤。在第290代、第313代接种物和肿瘤细胞中发现了两个染色体标记。
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