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大肠杆菌中三种分解代谢酶的同时诱导

Simultaneous induction of three catabolic enzymes in Escherichia coli.

作者信息

Pavlasová E, Stejskalová E, Sikyta B

出版信息

Folia Microbiol (Praha). 1980;25(3):201-6. doi: 10.1007/BF02877338.

DOI:10.1007/BF02877338
PMID:6249703
Abstract

During a simultaneous induction of three enzymes which are subject to catabolite repression (beta-galactosidase, tryptophanase and amylomaltase, or beta-galactosidase, tryptophanase and D-serine deaminase) in a batch culture, the rates of synthesis of beta-galactosidase and tryptophanase decreases, while the rates of synthesis of amylomaltase and D-serine deaminase remain unaffected. The addition of cAMP brings about a considerable increase of the rate of synthesis of D-serine deaminase and a partial synthesis rate increase of beta-galactosidase whihle the synthesis rate of tryptophanase remains lowered and the synthesis rate of amylomaltase remains unaffected. In a continuous culture beta-galactosidase, tryptophanase and D-serine deaminase are synthesized simultaneously at a maximum rate without mutual influence. The addition of cAMP increases the rate of synthesis of all three enzymes.

摘要

在分批培养中同时诱导三种受分解代谢物阻遏的酶(β-半乳糖苷酶、色氨酸酶和淀粉麦芽糖酶,或β-半乳糖苷酶、色氨酸酶和D-丝氨酸脱氨酶)时,β-半乳糖苷酶和色氨酸酶的合成速率降低,而淀粉麦芽糖酶和D-丝氨酸脱氨酶的合成速率不受影响。添加环磷酸腺苷(cAMP)会使D-丝氨酸脱氨酶的合成速率大幅增加,β-半乳糖苷酶的合成速率部分增加,而色氨酸酶的合成速率仍然降低,淀粉麦芽糖酶的合成速率不受影响。在连续培养中,β-半乳糖苷酶、色氨酸酶和D-丝氨酸脱氨酶以最大速率同时合成,互不影响。添加cAMP会增加这三种酶的合成速率。

相似文献

1
Simultaneous induction of three catabolic enzymes in Escherichia coli.大肠杆菌中三种分解代谢酶的同时诱导
Folia Microbiol (Praha). 1980;25(3):201-6. doi: 10.1007/BF02877338.
2
Effect of cyclic adenosine-3',5'-monophosphate on the simultaneous synthesis of beta-galactosidase and tryptophanase in Escherichia coli.3',5'-环磷酸腺苷对大肠杆菌中β-半乳糖苷酶和色氨酸酶同步合成的影响
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Gene-specific changes in induced enzyme synthesis in Escherichia coli infected with phage pX174.感染噬菌体pX174的大肠杆菌中诱导酶合成的基因特异性变化。
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本文引用的文献

1
[The biosynthesis of beta-galactosidase (lactase) in Escherichia coli; the specificity of induction].[大肠杆菌中β-半乳糖苷酶(乳糖酶)的生物合成;诱导的特异性]
Biochim Biophys Acta. 1951 Nov;7(4):585-99. doi: 10.1016/0006-3002(51)90072-8.
2
Induced formation of serine and threonine deaminases by Escherichia coli.大肠杆菌诱导丝氨酸和苏氨酸脱氨酶的形成。
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3
Effect of cyclic adenosine-3',5'-monophosphate on the simultaneous synthesis of beta-galactosidase and tryptophanase in Escherichia coli.
3',5'-环磷酸腺苷对大肠杆菌中β-半乳糖苷酶和色氨酸酶同步合成的影响
Folia Microbiol (Praha). 1980;25(1):16-23. doi: 10.1007/BF02876393.
4
Genetic analysis of the maltose A region in Escherichia coli.大肠杆菌中麦芽糖A区域的遗传分析。
J Bacteriol. 1969 May;98(2):559-67. doi: 10.1128/jb.98.2.559-567.1969.
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[Phenotypic expression and genetic localization of mutations affecting maltose metabolism in Escherichia coli K 12].[影响大肠杆菌K12麦芽糖代谢的突变的表型表达与基因定位]
Ann Inst Pasteur (Paris). 1967 Jun;112(6):673-98.
6
Role of adenosine 3',5'-cyclic monophosphate and its specific binding protein in the regulation of D-serine deaminase synthesis.3',5'-环磷酸腺苷及其特异性结合蛋白在D-丝氨酸脱氨酶合成调控中的作用。
J Bacteriol. 1973 Feb;113(2):781-5. doi: 10.1128/jb.113.2.781-785.1973.
7
Positive control in the D-serine deaminase system of Escherichia coli K-12.大肠杆菌K-12的D-丝氨酸脱氨酶系统中的阳性对照。
J Bacteriol. 1975 Mar;121(3):1092-101. doi: 10.1128/jb.121.3.1092-1101.1975.
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Simultaneous and gradual induction of beta-galactosidase and tryptophanase synthesis in an Escherichia coli batch culture.
Folia Microbiol (Praha). 1976;21(6):431-7. doi: 10.1007/BF02876933.
9
Specific in vivo cleavage of D-serine deaminase and properties of tetrameric polypeptide aggregates of the fragments.D-丝氨酸脱氨酶在体内的特异性裂解及裂解片段的四聚体多肽聚集体的性质
J Bacteriol. 1976 Apr;126(1):132-9. doi: 10.1128/jb.126.1.132-139.1976.
10
Simultaneous and successive induction of synthesis of beta-galactosidase and tryptophanase in Escherichia coli K 12 in the chemostat.在恒化器中对大肠杆菌K12同时及连续诱导β-半乳糖苷酶和色氨酸酶的合成。
Folia Microbiol (Praha). 1977;22(4):241-7. doi: 10.1007/BF02877652.