孤立性促肾上腺皮质激素缺乏症和原发性甲状腺功能减退症：低钠血症时抗利尿激素分泌的容量依赖性升高。
Isolated ACTH deficiency and primary hypothyroidism: volume-dependent elevation of antidiuretic hormone secretion in the presence of hyponatremia.
作者信息
Leroith D, Broitman D, Sukenik S, Glick S M
出版信息
Isr J Med Sci. 1980 Jun;16(6):440-3.
PMID:6249773
Abstract
The unusual combination of isolated deficiency of ACTH secretion and primary hypothyroidism was demonstrated in a 72-year-old man. Antidiuretic hormone (ADH) levels were elevated despite severe hyponatremia. This abnormality was corrected by salt replacement and hydrocortisone therapy. These results suggest that the elevated ADH levels were appropriate for the volume depletion caused by the hypoadrenalism and were not related to the hypothyroidism.
摘要
一名72岁男性被证实存在促肾上腺皮质激素（ACTH）分泌孤立性缺乏与原发性甲状腺功能减退的不寻常组合。尽管存在严重低钠血症，但抗利尿激素（ADH）水平仍升高。通过补充盐分和氢化可的松治疗纠正了这一异常。这些结果表明，ADH水平升高与肾上腺皮质功能减退引起的容量耗竭相适应，与甲状腺功能减退无关。
相似文献
1
2
Hyponatremia and inappropriate secretion of vasopressin (antidiuretic hormone) in patients with hypopituitarism.垂体功能减退患者的低钠血症和抗利尿激素（血管加压素）分泌不当。
N Engl J Med. 1989 Aug 24;321(8):492-6. doi: 10.1056/NEJM198908243210802.
3
[Hyponatremia, primary hypothyroidism and inadequate secretion of antidiuretic hormone].低钠血症、原发性甲状腺功能减退症与抗利尿激素分泌不足
Rev Clin Esp. 1997 Aug;197(8):593-4.
4
Differentiating appropriate antidiuretic hormone secretion, inappropriate antidiuretic hormone secretion and cerebral salt wasting: the common, uncommon, and misnamed.鉴别抗利尿激素正常分泌、抗利尿激素分泌不当及脑性盐耗综合征：常见、不常见及命名错误的情况。
Curr Opin Pediatr. 2008 Aug;20(4):448-52. doi: 10.1097/MOP.0b013e328305e403.
5
[Hyponatremia in syndrome of inappropiate antidiuretic hormone secretion--cases report].[抗利尿激素分泌异常综合征所致低钠血症——病例报告]
Pol Merkur Lekarski. 2008 Sep;25(147):247-9.
6
7
[Hyponatremia secondary to inappropriate antidiuretic hormone secretion].抗利尿激素分泌不当所致低钠血症
G Ital Nefrol. 2008 Sep-Oct;25(5):554-61.
8
[A case of isolated ACTH deficiency with a myopathy of rare type and hyponatremia].[一例伴有罕见类型肌病和低钠血症的孤立性促肾上腺皮质激素缺乏症]
Nihon Naika Gakkai Zasshi. 1985 Oct;74(10):1442-50.
9
10
[Severe hyponatremia, possibly due to inappropriate antidiuretic hormone secretion, during use of the antidepressant fluoxetine].[在使用抗抑郁药氟西汀期间出现严重低钠血症，可能因抗利尿激素分泌不当所致]
Ned Tijdschr Geneeskd. 1994 Jun 4;138(23):1181-3.
引用本文的文献
1
Effect of Optimal Thyroid Replacement Therapy on Chronic Hyponatremia with Focused Review of the Evidence, Mechanisms, and Clinical Implications.最佳甲状腺替代疗法对慢性低钠血症的影响：证据、机制及临床意义的重点综述
Cureus. 2019 Oct 1;11(10):e5813. doi: 10.7759/cureus.5813.
Zotero 插件