[在使用抗抑郁药氟西汀期间出现严重低钠血症，可能因抗利尿激素分泌不当所致]
[Severe hyponatremia, possibly due to inappropriate antidiuretic hormone secretion, during use of the antidepressant fluoxetine].
作者信息
ten Holt W L, Klaassen C H, Schrijver G
机构信息
Rode Kruis Ziekenhuis, afd. Interne Geneeskunde, Beverwijk.
出版信息
Ned Tijdschr Geneeskd. 1994 Jun 4;138(23):1181-3.
PMID:8008142
Abstract
In a 78-year-old female with hyponatraemia, the syndrome of inappropriate ADH secretion as a side effect of fluoxetine, a relatively new antidepressive drug, was tentatively diagnosed. In the literature 14 cases of this adverse reaction have been described. One should be careful when prescribing fluoxetine to elderly persons, notably when a diuretic is prescribed as well.
摘要
在一名患有低钠血症的78岁女性中，初步诊断为不适当抗利尿激素分泌综合征，这是一种相对较新的抗抑郁药氟西汀的副作用。文献中已描述了14例这种不良反应。给老年人开氟西汀时应谨慎，尤其是同时开利尿剂时。
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