Ménard D
Histochemistry. 1980;67(1):53-64. doi: 10.1007/BF00490087.
The development of the endoplasmic reticulum (ER) and the ultrastructural localization of glucose-6-phosphatase activity have been studied in the proximal jejunum and distal ileum during the postnatal period. One day after birth, the amount and the repartition of ER in the jejunal enterocytes are similar to that observed in postweaning period. In the following days an extensive proliferation of SER is noted in the supranuclear zone of the absorbing cells. From day 7 till postweaning period a gradual decrease of the amount of SER is observed and after weaning, the ultrastructure of the enterocytes is similar to that in the adult mouse enterocytes. At all time, a positive reaction for G-6-Pase activity is observed in the cisternae of the endoplasmic reticulum and in the nuclear envelope. In the distal ileum, the SER is poorly developed one day after birth. During the first two weeks, the ER increases but no extensive proliferation of SER can be noted as in the jejunum. The G-6-Pase activity can be visualized in the rough and smooth endoplasmic reticulum as well as in the nuclear envelope. It appears that the proliferation of SER could be interpreted as the morphologic expression of an increased G-6-Pase activity.
在出生后的一段时间内，研究了空肠近端和回肠远端内质网（ER）的发育以及葡萄糖-6-磷酸酶活性的超微结构定位。出生后一天，空肠肠细胞中内质网的数量和分布与断奶后观察到的相似。在接下来的几天里，吸收细胞核上区的滑面内质网（SER）大量增殖。从第7天到断奶期，SER的数量逐渐减少，断奶后，肠细胞的超微结构与成年小鼠肠细胞相似。在所有时间里，内质网池和核膜中均观察到葡萄糖-6-磷酸酶（G-6-Pase）活性呈阳性反应。在回肠远端，出生后一天SER发育不良。在最初的两周内，内质网增加，但未观察到如空肠中SER的大量增殖。G-6-Pase活性可见于粗面和滑面内质网以及核膜。似乎SER的增殖可解释为G-6-Pase活性增加的形态学表现。
