Ogura J H, Toomey J M, Setzen M, Sobol S
Laryngoscope. 1980 Sep;90(9):1429-40.
Eight cases, the largest series of malignant fibrous histiocytomas of the head and neck to date, are reported. In over one-half of the cases, the initial problems encountered in the case made the true diagnosis misleading. For correct diagnosis multiple biopsies may be required. The diagnosis is further confirmed by the clinical behavior of the tumor and its site, size, and depth of involvement. Four specific histopathologic variants are described. Wide surgical excision is the preferrred treatment. The potential role of adjunctive irradiation should be considered.
本文报告了8例病例，这是迄今为止头颈部恶性纤维组织细胞瘤数量最多的一组病例。在超过半数的病例中，最初遇到的问题导致做出了误导性的诊断。为了做出正确诊断，可能需要进行多次活检。肿瘤的临床行为及其部位、大小和受累深度进一步证实了诊断。文中描述了四种特定的组织病理学变体。广泛手术切除是首选的治疗方法。应考虑辅助放疗的潜在作用。
