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用二巯基丁二酸(DMSA)进行延迟扫描:相对肾血浆流量的一个简单指标。

Delayed scanning with DMSA: a simple index of relative renal plasma flow.

作者信息

Taylor A

出版信息

Radiology. 1980 Aug;136(2):449-53. doi: 10.1148/radiology.136.2.6250197.

DOI:10.1148/radiology.136.2.6250197
PMID:6250197
Abstract

Relative renal uptake of 99mTc-dimercaptosuccinic acid (DMSA) was compared with the relative effective renal plasma flow (ERPF) to each kidney. In 25 patients with serum creatinine less than or equal to 2.0 mg/dl, there was excellent agreement when the regions of interest were assigned by a computer. In 10 patients with serum creatinine greater than 2.0 mg/dl, agreement was poor. A 24-hour image is sufficient to obtain such data. In patients with renal failure, this technique may give inaccurate results due to high tissue background activity; moreover, since it reflects the current functioning status of the kidney, it should not be used to predict recoverable function in patients with acute or unstable renal disease.

摘要

比较了99mTc-二巯基丁二酸(DMSA)的相对肾摄取与每个肾脏的相对有效肾血浆流量(ERPF)。在25例血清肌酐小于或等于2.0mg/dl的患者中,当通过计算机指定感兴趣区域时,两者具有极佳的一致性。在10例血清肌酐大于2.0mg/dl的患者中,一致性较差。一张24小时的图像足以获得此类数据。在肾衰竭患者中,由于组织本底活性较高,该技术可能会给出不准确的结果;此外,由于它反映的是肾脏当前的功能状态,因此不应将其用于预测急性或不稳定肾病患者的可恢复功能。

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1
Delayed scanning with DMSA: a simple index of relative renal plasma flow.用二巯基丁二酸(DMSA)进行延迟扫描:相对肾血浆流量的一个简单指标。
Radiology. 1980 Aug;136(2):449-53. doi: 10.1148/radiology.136.2.6250197.
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2
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The effect of radiopharmaceutical choice on the assessment of the relative renal function in upper urinary tract obstruction.
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