In vitro suppression of normal granulocytic stem cells by inhibitory activity derived from human leukemia cells.

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作者信息

Broxmeyer H E, Jacobsen N, Kurland J, Mendelsohn N, Moore A S

出版信息

J Natl Cancer Inst. 1978 Mar;60(3):497-511. doi: 10.1093/jnci/60.3.497.

DOI:10.1093/jnci/60.3.497

PMID:625060

Abstract

摘要

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In vitro suppression of normal granulocytic stem cells by inhibitory activity derived from human leukemia cells.

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Interaction between normal and leukaemic human cells in agar culture.人正常细胞与白血病细胞在琼脂培养中的相互作用。

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An in vitro demonstration of the ability of human bone marrow stromal elements to sustain granulocytopoiesis.人骨髓基质成分维持粒细胞生成能力的体外证明。

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Effects of murine leukemia virus infection on long-term hematopoiesis in vitro emphasized by increased survival of bone marrow cultures derived from BALB/Mo mice.鼠白血病病毒感染对体外长期造血的影响通过源自BALB/Mo小鼠的骨髓培养物存活率增加得以凸显。

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Granulopoiesis inhibition in acute inflammation: comparative studies in healthy and leukaemic mice.急性炎症中的粒细胞生成抑制：健康和白血病小鼠的比较研究。

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Identification of leukemia-associated inhibitory activity as acidic isoferritins. A regulatory role for acidic isoferritins in the production of granulocytes and macrophages.鉴定白血病相关抑制活性为酸性异铁蛋白。酸性异铁蛋白在粒细胞和巨噬细胞产生中的调节作用。

J Exp Med. 1981 Jun 1;153(6):1426-44. doi: 10.1084/jem.153.6.1426.

Chronic myelogenous leukemia: in vitro studies of hematopoietic regulation in a patient undergoing intensive chemotherapy.慢性粒细胞白血病：对一名接受强化化疗患者造血调控的体外研究

J Clin Invest. 1981 Jun;67(6):1593-8. doi: 10.1172/jci110193.

Association between colony forming units-granulocyte macrophage expression of Ia-like (HLA-DR) antigen and control of granulocyte and macrophage production. A new role for prostaglandin E.集落形成单位-粒细胞巨噬细胞Ia样（HLA-DR）抗原的表达与粒细胞和巨噬细胞生成的调控之间的关联。前列腺素E的新作用。

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HLA-DR human histocompatibility leukocyte antigens-restricted lymphocyte-monocyte interactions in the release from monocytes of acidic isoferritins that suppress hematopoietic progenitor cells.HLA - DR（人类组织相容性白细胞抗原）限制的淋巴细胞与单核细胞相互作用，导致单核细胞释放酸性异铁蛋白，而这种酸性异铁蛋白会抑制造血祖细胞。

J Clin Invest. 1984 Apr;73(4):939-53. doi: 10.1172/JCI111318.

Relationship of cell-cycle expression of Ia-like antigenic determinants on normal and leukemia human granulocyte-macrophage progenitor cells to regulation in vitro by acidic isoferritins.正常及白血病人类粒细胞-巨噬细胞祖细胞上Ia样抗原决定簇的细胞周期表达与酸性异铁蛋白体外调节的关系。

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