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携带YC8淋巴瘤小鼠的尿糖脂:糖基化过程的效应物

Urinary glycolipids of YC8 lymphoma bearing mice: effectors of glycosylation process.

作者信息

Achy-Sachot N, Turpin M, Morel E

出版信息

Biomedicine. 1980 Apr;33(2):56-8.

PMID:6250651
Abstract

Glycolipids from YC8 lymphoma bearing mice urines have peen obtained by the method of Folch and fractionated on silicic column and on silica gel plates. One fraction, among the five obtained, may be used by sera galactosyltransferase as an acceptor for galactose, to form a new glycolipid compound. Furthermore this fraction has shown an inhibitory effect on phosphatase activity, in agreement with hypothesis which relates relates glycosyltransferase and phosphatase activities during tumorous process.

摘要

通过Folch方法从携带YC8淋巴瘤的小鼠尿液中获得糖脂,并在硅胶柱和硅胶板上进行分离。在获得的五个组分中,有一个组分可被血清半乳糖基转移酶用作半乳糖的受体,以形成一种新的糖脂化合物。此外,该组分已显示出对磷酸酶活性的抑制作用,这与肿瘤发生过程中糖基转移酶和磷酸酶活性相关的假设一致。

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