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Isolation and characterization of a mutant of Escherichia coli K12 synthesizing DNA polymerase I and endonuclease I constitutively.

作者信息

Ahmad S I, Atkinson A, Eisenstark A

出版信息

J Gen Microbiol. 1980 Apr;117(2):419-22. doi: 10.1099/00221287-117-2-419.

DOI:10.1099/00221287-117-2-419
PMID:6252282
Abstract

A mutant of Escherichia coli K12, highly resistant to ultraviolet radiation, has been isolated. Preliminary tests show that this mutant is also resistant to mitomycin C, nalidixic acid, fluorouracil and thymineless death. The mutant strain apparently repairs its damaged DNA more efficiently than wild-type E. coli K12 strains and, to do so, constitutively produces 35 times more DNA polymerase I and 12 times more endonuclease I than the wild-type strain.

摘要

相似文献

1
Isolation and characterization of a mutant of Escherichia coli K12 synthesizing DNA polymerase I and endonuclease I constitutively.
J Gen Microbiol. 1980 Apr;117(2):419-22. doi: 10.1099/00221287-117-2-419.
2
Effect of the uvrD3 mutation on ultraviolet radiation-induced DNA-repair replication in Escherichia coli K12.uvrD3突变对大肠杆菌K12中紫外线诱导的DNA修复复制的影响。
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Inducible DNA polymerase I synthesis in a UV hyper-resistant mutant of Escherichia coli.大肠杆菌紫外线超抗性突变体中可诱导的DNA聚合酶I合成
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[Escherichia coli K-12 mutants with increased resistance to ionizing radiation. V. The effect of mutations on spontaneous and radiation mutagenesis].[对电离辐射抗性增强的大肠杆菌K-12突变体。V. 突变对自发诱变和辐射诱变的影响]
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Mutations to nitrofurantoin and nitrofurazone resistance in Escherichia coli K12.大肠杆菌K12中对呋喃妥因和呋喃西林耐药性的突变
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Radiat Res. 1992 Dec;132(3):334-8.

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