Goodwin W J, Jesse R H
Arch Otolaryngol. 1980 Nov;106(11):675-9. doi: 10.1001/archotol.1980.00790350017006.
In a review of 136 patients with squamous cell, basal cell, and salivary gland cancers involving the external auditory canal and temporal bone, the majority of patients had received prior treatment and came to us with recurrent tumor. Squamous cell carcinoma of the concha and cartilaginous ear canal behaved aggressively. Five-year survival in 35 patients with deep temporal bone involvement was 29%. The major reason for failure in this group was incomplete resection of disease. Postoperative irradiation was of no benefit when the cancer could not be completely excised. When compared with surgery alone, combined therapy with postoperative irradiation did improve local control in patients with completely resected lesions but did not demonstrate a corresponding increase in five-year survival.
在一项对136例患有累及外耳道和颞骨的鳞状细胞癌、基底细胞癌及涎腺癌患者的回顾性研究中,大多数患者之前已接受过治疗,前来我们这里时肿瘤已复发。耳廓和软骨性耳道的鳞状细胞癌侵袭性较强。35例有颞骨深部受累的患者的5年生存率为29%。该组治疗失败的主要原因是疾病切除不完全。当癌症无法完全切除时,术后放疗并无益处。与单纯手术相比,术后放疗的联合治疗确实改善了完全切除病变患者的局部控制,但未显示出5年生存率相应提高。