Niilo L
Can Vet J. 1980 May;21(5):141-8.
The diseases caused by various types of Clostridium perfringens are critically reviewed in the light of current knowledge. Particular emphasis is placed on information concerning these diseases in Canadian livestock. There are two etiologically clearly-defined acute C. perfringens diseases recognized in Canada: hemorrhagic enteritis of the new born calf, caused by C. perfringens type C, and enterotoxemia of sheep, caused by type D. Clostridium perfringens type A may play a role as a secondary pathological agent in various disease conditions, such as necrotic enteritis of chickens. It may also cause wound infections and may provide a source for human food poisoning outbreaks. There appears to be a considerable lack of knowledge regarding the distribution of C. perfringens types, their pathogenesis, diagnosis and the incidence of diseases caused by this organism.
根据现有知识,对由各种类型的产气荚膜梭菌引起的疾病进行了批判性综述。特别强调了加拿大牲畜中有关这些疾病的信息。在加拿大,有两种病因明确的急性产气荚膜梭菌疾病:由C型产气荚膜梭菌引起的新生犊牛出血性肠炎,以及由D型引起的绵羊肠毒血症。A型产气荚膜梭菌可能在各种疾病状况中作为继发性病原体发挥作用,例如鸡的坏死性肠炎。它还可能引起伤口感染,并可能成为人类食物中毒暴发的源头。关于产气荚膜梭菌各型的分布、它们的发病机制、诊断以及由该微生物引起的疾病发病率,似乎存在相当大的知识空白。