Renoux M, Bernard J F, Dhermy D, Amar M, Vroclans M, Boivin P
Sem Hop. 1980 Oct 15;56(37-38):1486-8.
Acute agranulocytosis is a serious accident if the nature of the accident and the responsible drug are ignored or if it happens to a weak patient. Among thirty two cases of hospitalization, probably chosen according to their seriousness, the authors recall the diversity of the symptoms, the risk of the abuse of the "pyrazol compound" (70% of agranulocytosis) and the frequency of relapse (30%). The prognosis depends on the risk of infection. Septicemy is rare (15%), often foreseeable depending on the state of the patient. Agranulocytosis remains serious in spite of a wide range antibiotics administered in the early stages.
如果忽视急性粒细胞缺乏症这一意外事件的性质及其相关药物,或者该事件发生在体弱患者身上,那么它就是一个严重的情况。在32例住院病例中(可能是根据病情严重程度挑选出来的),作者回顾了症状的多样性、“吡唑化合物”滥用的风险(粒细胞缺乏症患者中有70%与此有关)以及复发频率(30%)。预后取决于感染风险。败血症很少见(15%),通常根据患者的状况是可预见的。尽管在早期阶段使用了多种抗生素,但粒细胞缺乏症仍然很严重。