Morens D M, Bregman D J, West C M, Greene M H, Mazur M H, Dolin R, Fisher R I
Ann Intern Med. 1980 Sep;93(3):414-9. doi: 10.7326/0003-4819-93-3-414.
An outbreak of varicella-zoster infection occurred among patients of the Medicine Branch, National Cancer Institute, National Institutes of Health. Epidemiologic investigation suggested that the outbreak was due to two distinct types of disease. One type was acquired without previous exposure to other diseased patients and invariably associated with dermatomal lesions. The other, an a typical form, was associated with person-to-person transmission and equivocal initial dermatomal distribution and had an incubation period of approximately 11 to 25 days. Despite the diagnosis of zoster, the latter probably was varicella, occurring in patients who were immunodeficient because of disease, debility, and chemotherapy.
美国国立卫生研究院国立癌症研究所医学科的患者中发生了水痘-带状疱疹感染暴发。流行病学调查表明,此次暴发是由两种不同类型的疾病引起的。一种类型是在没有先前接触其他患病患者的情况下获得的,并且总是与皮节病变相关。另一种是非典型形式,与人传人传播、初始皮节分布不明确有关,潜伏期约为11至25天。尽管诊断为带状疱疹,但后者可能是水痘,发生在因疾病、虚弱和化疗而免疫功能低下的患者中。