Lucio B, Hitchner S B
Avian Dis. 1980 Apr-Jun;24(2):334-44.
The response of mibolerone-treated chickens to infectious bursal disease virus (IBDV) was studied. Chickens fed a ration containing mibolerone at 1.5 parts per million (ppm) developed bursal atrophy by 4 weeks of age. No indication was found that mibolerone prevented IBDV infection even after 7 weeks of feeding. Furthermore, only chickens treated with mibolerone died when infected with IBDV at 2 or 3 weeks of age, and treated chickens had more severe clinical signs than did untreated controls when infected at 4-8 weeks of age. Chickens fed mibolerone had lower body weights than unmedicated controls, and apparently had a lower antibody response to IBDV and to bovine serum albumin.
研究了用米勃酮处理的鸡对传染性法氏囊病病毒（IBDV）的反应。饲喂含百万分之一百五十（ppm）米勃酮日粮的鸡在4周龄时出现法氏囊萎缩。即使在饲喂7周后，也未发现米勃酮能预防IBDV感染的迹象。此外，仅在2或3周龄时感染IBDV的用米勃酮处理的鸡死亡，而在4至8周龄时感染的情况下，经处理的鸡比未处理的对照鸡具有更严重的临床症状。饲喂米勃酮的鸡体重低于未用药的对照鸡，并且显然对IBDV和牛血清白蛋白的抗体反应较低。
