Thulin T, Bengtsson B, Scherstén B
Postgrad Med J. 1978 Jan;54(627):10-5. doi: 10.1136/pgmj.54.627.10.
All residents in a suburban community in southern Sweden, 8 years of age and older, were invited to an ophthalmological examination. The examination included a blood pressure determination. Of the 1917 persons invited 85·5% took part in the study. 3·5% of these were excluded because they were taking antihypertensive drugs. The investigations were conducted during 14 consecutive months and at different times of the day. The systolic and diastolic blood pressure distribution curves exhibited a positive skewing. The blood pressures rose to a plateau with essentially unchanged pressures in the age groups 28-32 years up to 38-42 years. In these ages, the systolic blood pressure was significantly higher among the males than among the females. The relation was reversed in the age groups above 48 years. The diastolic blood pressure showed no significant sex differences in the various age groups. A multiple linear regression analysis was used to determine whether there were diurnal and seasonal effects on the blood pressure independent of the age and sex. The systolic blood pressure during the winter months was 4·1 and 5·0 mmHg higher in the male and female subjects respectively, while the diastolic blood pressure during the winter months was 1·7 and 1·9 mmHg higher in the male and female subjects respectively. The time of day had no effect on the systolic blood pressure while the diastolic blood pressure increased by 0·24 and 0·27 mmHg/hr from 8 a.m. to 9 p.m. in the male and female subjects respectively. It is concluded that the small genuine effects of the time of measurement of casual blood pressure lack practical importance in screening of hypertension.
瑞典南部一个郊区社区中所有8岁及以上的居民都被邀请参加眼科检查。该检查包括血压测定。在1917名被邀请者中,85.5%的人参与了这项研究。其中3.5%的人被排除,因为他们正在服用抗高血压药物。调查在连续14个月内的不同时间段进行。收缩压和舒张压分布曲线呈正偏态。血压在28 - 32岁至38 - 42岁年龄组中上升至平稳状态,血压基本保持不变。在这些年龄段,男性的收缩压显著高于女性。在48岁以上年龄组中,这种关系则相反。舒张压在各年龄组中未显示出显著的性别差异。采用多元线性回归分析来确定血压是否存在独立于年龄和性别的昼夜及季节效应。在冬季,男性和女性受试者的收缩压分别高出4.1 mmHg和5.0 mmHg,而舒张压分别高出1.7 mmHg和1.9 mmHg。一天中的时间对收缩压没有影响,而男性和女性受试者的舒张压从上午8点到晚上9点分别每小时升高0.24 mmHg和0.27 mmHg。结论是,在筛查高血压时,随机血压测量时间的微小实际影响缺乏实际重要性。