Yamamoto T, Jo T, Ishibashi T
Postgrad Med J. 1978 Jan;54(627):40-2. doi: 10.1136/pgmj.54.627.40.
A 47-year-old woman with phaeochromocytoma showed blood pressure changes characterized by the regular appearance of hypertension at night. The urinary excretion of catecholamines and their metabolites showed augmentation roughly parallel with the elevation of the blood pressure. During normotensive periods, the urinary excretion of catecholamines and their metabolites was elevated. The findings suggested that the pressor effect of catecholamine hypersecretion was compromised to a certain degree and that the regular nocturnal appearances of hypertensive paroxysm conceivably resulted from a spontaneous cyclic augmentation of the catecholamine secretion from the tumour.
一名患有嗜铬细胞瘤的47岁女性表现出血压变化，其特征为夜间规律性出现高血压。儿茶酚胺及其代谢产物的尿排泄量大致与血压升高呈平行增加。在血压正常期间，儿茶酚胺及其代谢产物的尿排泄量也升高。这些发现提示，儿茶酚胺分泌过多的升压作用在一定程度上受到损害，夜间规律性出现的高血压发作可能是由于肿瘤儿茶酚胺分泌的自发性周期性增加所致。
