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Increased high-molecular-weight thyrotropin with impaired biologic activity in a euthyroid man.

作者信息

Spitz I M, Le Roith D, Hirsch H, Carayon P, Pekonen F, Liel Y, Sobel R, Chorer Z, Weintraub B

出版信息

N Engl J Med. 1981 Jan 29;304(5):278-82. doi: 10.1056/NEJM198101293040506.

DOI:10.1056/NEJM198101293040506
PMID:6255331
Abstract
摘要

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Increased high-molecular-weight thyrotropin with impaired biologic activity in a euthyroid man.
N Engl J Med. 1981 Jan 29;304(5):278-82. doi: 10.1056/NEJM198101293040506.
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Thyrotropin regulation of adenylate cyclase activity in human thyroid neoplasms.促甲状腺素对人甲状腺肿瘤中腺苷酸环化酶活性的调节
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Preparation of radiolabeled thyroid-stimulating immunoglobulins (TSI) by recombining TSI heavy chains with 125I-labeled light chains: direct evidence that the product binds to the membrane thyrotropin receptor and stimulates adenylate cyclase.通过将促甲状腺素免疫球蛋白（TSI）重链与125I标记的轻链重组来制备放射性标记的促甲状腺素免疫球蛋白（TSI）：该产物与膜促甲状腺激素受体结合并刺激腺苷酸环化酶的直接证据。
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Decreased receptor binding of biologically inactive thyrotropin in central hypothyroidism. Effect of treatment with thyrotropin-releasing hormone.
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Unexplained high thyroid stimulating hormone: a "BIG" problem.不明原因的促甲状腺激素升高：一个“重大”问题。
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.01.2009.1474. Epub 2009 Apr 14.
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Postgrad Med J. 1986 Jun;62(728):477-80. doi: 10.1136/pgmj.62.728.477.
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Intrinsic bioactivity of thyrotropin in human serum is inversely correlated with thyroid hormone concentrations. Application of a new bioassay using the FRTL-5 rat thyroid cell strain.人血清中促甲状腺激素的内在生物活性与甲状腺激素浓度呈负相关。使用FRTL-5大鼠甲状腺细胞系的一种新生物测定法的应用。
J Clin Invest. 1987 May;79(5):1388-94. doi: 10.1172/JCI112966.
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Exaggerated and prolonged thyrotrophin releasing hormone (TRH) test responses in tertiary hypothyroidism.三发性甲状腺功能减退症中促甲状腺激素释放激素（TRH）试验反应的过度和延长
J Clin Pathol. 1991 Jun;44(6):522-3. doi: 10.1136/jcp.44.6.522.