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传染性腔上囊病暴发的计算机模拟。IV. 改变鸡群规模、年龄和免疫力,通过G-4模式获得的流行情况。

Computer simulation of Gumboro disease outbreak. IV. Epizootics obtained by mode G-4 with flock size, age and immunity changed.

作者信息

Takizawa T, Ito T, Tanaka T, Mizumura Y

出版信息

Natl Inst Anim Health Q (Tokyo). 1980 Summer;20(2):68-74.

PMID:6255347
Abstract

For the computer simulation of Gumboro disease outbreak by Model G-4 a program was written in FORTRAN. Of over twenty parameters involved in the model, the following three were used as input variables: (1) age of chickens at housing a1 (= 1 and 21); (2) size of flock at housing, N(a1) (= 100 and 1,000); and (3) geometric mean of the level of parentally conferred immunity at hatching, G(1) (= 0, 2, 8, and 32). The outputs were the graphic images demonstrating the chronological changes in a flock of innate resistance, parentally conferred immunity, and their sum, and the epizootic patterns composed of numbers of chickens at subclinical stage, clinically diseased, recovered, condemned, etc. at each age. As a result, stronger epizootics were produced at a lower level of parentally conferred immunity, and a higher age and a larger size of flocks. It was suggested that the subclinical stage might not be understood as an inapparent infection, and that a further postulate on the infection might be necessary to be introduced into this model to increase the practical utility, as well as the theoretical soundness, of this series of studies.

摘要

为了通过G - 4模型对传染性法氏囊病疫情进行计算机模拟,用FORTRAN语言编写了一个程序。在该模型涉及的二十多个参数中,以下三个被用作输入变量:(1) 入舍时鸡的年龄a1(= 1和21);(2) 入舍时鸡群规模,N(a1)(= 100和1000);以及(3) 孵化时母源抗体水平的几何平均值,G(1)(= 0、2、8和32)。输出结果是展示鸡群先天抵抗力、母源抗体及其总和随时间变化的图形图像,以及由各年龄段处于亚临床阶段、临床发病、康复、被淘汰等状态的鸡只数量组成的流行模式。结果表明,在母源抗体水平较低、鸡龄较大和鸡群规模较大时会产生更严重的疫情。研究表明,亚临床阶段可能不能被理解为隐性感染,并且可能需要在该模型中引入关于感染的进一步假设,以提高这一系列研究的实际效用和理论合理性。

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