果蝇中膜电兴奋性的促进作用。
Facilitation of membrane electrical excitability in Drosophila.
作者信息
Salkoff L, Wyman R
出版信息
Proc Natl Acad Sci U S A. 1980 Oct;77(10):6216-20. doi: 10.1073/pnas.77.10.6216.
Abstract
Prior electrical activity in the indirect flight muscles of Drosophila facilitates membrane excitability. The mechanism of facilitation involves the inactivation of an early, fast, transient outward current by prior membrane depolarizaton. In the facilitated state the calcium-dependent spike-like response has a decreased current and voltage threshold. The facilitated state persists for 1.5 sec after a membrane active response. A single nerve-driven spike is sufficient to facilitate membrane excitability.
摘要
果蝇间接飞行肌中先前的电活动促进膜兴奋性。促进机制涉及先前的膜去极化使早期、快速、短暂的外向电流失活。在促进状态下，钙依赖性尖峰样反应的电流和电压阈值降低。膜主动反应后促进状态持续1.5秒。单个神经驱动的尖峰足以促进膜兴奋性。
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