Oehme P
Z Gesamte Inn Med. 1980 Jul 15;35(14):20-5.
A survey is given on the actual state of drug research and its developmental tendencies. Issuing from an estimation of the present and prospective health-political and economic importance of the drugs the following main subjects of drug research are represented:--Influence on drug research by progressing of knowledge from biosciences,--traditional cooperation between synthesis, chemistry and biological test,--problems in the judgment of activity and security in the application of drugs (indirect side-effects of drugs),--problems in clinical testing of new drugs,--drug monitoring,--biopharmaceutical and galenic research conceptions. As to the fields mentioned the developmental tendencies are described as well as possible effects on the medicamentous therapy in practice are treated.
本文对药物研究的现状及其发展趋势进行了综述。从对药物当前和未来健康政治及经济重要性的评估出发,介绍了药物研究的以下主要主题:——生物科学知识进步对药物研究的影响,——合成、化学与生物测试之间的传统合作,——药物应用中活性和安全性判断方面的问题(药物的间接副作用),——新药临床试验中的问题,——药物监测,——生物制药和药剂学研究概念。针对上述领域,描述了其发展趋势,并探讨了对实际药物治疗可能产生的影响。