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[经胎盘给予性激素后大鼠的胚胎发生及出生后早期发育]

[Embryogenesis and early postnatal development of rats following transplacental sex hormone administration].

作者信息

Ird E A, Smirnova I O

出版信息

Biull Eksp Biol Med. 1980 Nov;90(11):607-9.

PMID:6256027
Abstract

A study was made of the effect of different doses of testosterone propionate, sinestrol, diethylstilbestrol and sigetin administered to rats during the last three days of pregnancy on the embryogenesis and postnatal development of the progeny. It was established that sex hormones (except sigetin) often disturb pregnancy, labor and lactation. They also exert a musculinizing and sterilizing effect on the progeny. Sigetin produces no action on embryogenesis or postnatal development of rats.

摘要

一项关于在妊娠最后三天给大鼠注射不同剂量丙酸睾酮、己烷雌酚、己烯雌酚和西盖替林对后代胚胎发育和产后发育影响的研究。结果表明,性激素(西盖替林除外)常常干扰妊娠、分娩和哺乳。它们还对后代产生雄性化和绝育作用。西盖替林对大鼠的胚胎发育或产后发育没有影响。

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