Korzhova V V, Lisitsyna N T, Mikhaĭlova E G
Biull Eksp Biol Med. 1981 Feb;91(2):184-5.
Ampicillin administration during pregnancy exerted no toxic effect on the developing fetus. However, it decreased the body weight of the progeny and the weight of the placenta. Oxacillin had an adverse effect on the pregnancy, labor, fetus and newborn. It is inferred that ampicillin can be used for treatment purposes at any time of the pregnancy whilst oxacillin administration might involve a high risk for the mother, fetus and newborn.
孕期使用氨苄西林对发育中的胎儿无毒性作用。然而,它降低了后代的体重和胎盘重量。苯唑西林对妊娠、分娩、胎儿及新生儿有不良影响。据推断,孕期任何时候均可使用氨苄西林进行治疗,而使用苯唑西林可能对母亲、胎儿及新生儿有高风险。