Young W S, Kuhar M J
Eur J Pharmacol. 1980 Oct 31;67(4):493-5. doi: 10.1016/0014-2999(80)90194-6.
The location of alpha 2-adrenergic receptors has been investigated in the guinea pig kidney. We used an in vitro labeling autoradiographic technique to examine the distribution of specific [3H]clonidine binding sites with the light microscope. alpha 2-Adrenergic receptors appeared to be located predominantly on the proximal tubules. The implication of this finding for renal physiology is discussed.
已经对豚鼠肾脏中α2-肾上腺素能受体的位置进行了研究。我们使用体外标记放射自显影技术，通过光学显微镜检查特异性[3H]可乐定结合位点的分布。α2-肾上腺素能受体似乎主要位于近端小管上。讨论了这一发现对肾脏生理学的意义。
