Derre M, Tubiana N, Carcassonne Y
Sem Hop. 1980;56(47-68):1999-2003.
Lymphocyte surface immunoglobulin, E-rosettes and EAC-rosettes were studied in 91 patients with chronic lymphocytic leukemia of well differentiated lymphosarcoma and 16 patients with poor differentiated lymphosarcoma (including lymphoblastic lymphoma and histiocytic lymphoma of Rappaport). The tests were performed on the malignant cells in peripheral blood or in lymph nodes. In well differentiated proliferation only one had T malignant cells. All the others had B malignant cells. In poor differentiated proliferation: 50 per cent of cases had "B" lymphosarcoma cells, 21 per cent of cases had "T" lymphosarcoma cells, 29 per cent of cases had "non T, non B" lymphosarcoma cells. These results show the heterogeneity of both functional aspects and stages of maturation in lymphoma cells.
对91例高分化淋巴细胞肉瘤型慢性淋巴细胞白血病患者和16例低分化淋巴细胞肉瘤患者（包括Rappaport的淋巴母细胞淋巴瘤和组织细胞淋巴瘤）进行了淋巴细胞表面免疫球蛋白、E花环和EAC花环研究。检测在外周血或淋巴结中的恶性细胞上进行。在高分化增殖中，仅1例有T恶性细胞，其他均为B恶性细胞。在低分化增殖中：50%的病例有“B”淋巴细胞肉瘤细胞，21%的病例有“T”淋巴细胞肉瘤细胞，29%的病例有“非T、非B”淋巴细胞肉瘤细胞。这些结果显示了淋巴瘤细胞在功能方面和成熟阶段的异质性。
