Clarke J K, Robertson G M, Purcell D A
Aust Vet J. 1980 Sep;56(9):424-8. doi: 10.1111/j.1751-0813.1980.tb02635.x.
Day-old chickens were vaccinated with the SA2 strain of infectious laryngotracheitis vaccine using a coarse spray and 14-day-old chickens were vaccinated using a coarse or a fine (Turbair Vaccinair 240) spray. The Conjunctiva was the most common site of infection in all cases but this almost invariably led to involvement of the nasolacrimal ducts. Other sites in the nasal cavity were affected less frequently. The clinical consequences of infection in day-old chickens were too severe for field use but the mortality (0 to 1.4% in different experiments) in 14-day-old chickens may be acceptable in some circumstances although about 9% developed infection of the trachea. It is concluded that a less pathogenic vaccine is needed if spray vaccination with ILT is to be recommended as a routine procedure particularly for day-old chickens.
一日龄雏鸡使用粗喷雾器接种传染性喉气管炎疫苗SA2株，14日龄雏鸡使用粗喷雾器或细喷雾器（Turbair Vaccinair 240）接种。在所有病例中，结膜是最常见的感染部位，但这几乎总是导致鼻泪管受累。鼻腔的其他部位受影响的频率较低。一日龄雏鸡感染的临床后果对实际应用来说过于严重，但14日龄雏鸡的死亡率（在不同实验中为0至1.4%）在某些情况下可能是可以接受的，尽管约9%的雏鸡发生了气管感染。得出的结论是，如果要推荐将传染性喉气管炎喷雾免疫作为常规程序，特别是对一日龄雏鸡，需要一种致病性较低的疫苗。
