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[使用洛哌丁胺治疗恶性腹部肿瘤钴远距离照射后腹泻患者的研究(作者译)]

[Studies using loperamide in patients with diarrhea following telecobalt irradiation of malignant abdominal tumors (author's transl)].

作者信息

Geginat G, Behdjati F, Green E, Kaeferstein D

出版信息

Strahlentherapie. 1978 Jan;154(1):11-5.

PMID:625768
Abstract

45 patients with diarrheas appearing after exposure of the gastro-intestinal region to ionizing radiation were given loperamide in the course of a study. A few days after administration of the loperamide, normalization of the stools took place, except in three cases. Simultaneous tenesmic gripes, some of the patients had also suffered from, disappeared completely, with the exception of two cases where, however, normalization of the stools was obtained by means of the loperamide therapy. Subjective side-effects did not occur. Also no alterations of the blood count, hematological features, liver function tests or urine have been observed.

摘要

在一项研究过程中,45名胃肠道接受电离辐射后出现腹泻的患者服用了洛哌丁胺。服用洛哌丁胺几天后,除3例患者外,大便恢复正常。一些患者同时出现的里急后重性绞痛也完全消失,只有2例除外,不过这2例患者通过洛哌丁胺治疗后大便恢复了正常。未出现主观副作用。血液计数、血液学特征、肝功能检查或尿液也未观察到变化。

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