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[使用洛哌丁胺治疗恶性腹部肿瘤钴远距离照射后腹泻患者的研究(作者译)]

[Studies using loperamide in patients with diarrhea following telecobalt irradiation of malignant abdominal tumors (author's transl)].

作者信息

Geginat G, Behdjati F, Green E, Kaeferstein D

出版信息

Strahlentherapie. 1978 Jan;154(1):11-5.

PMID:625768
Abstract

45 patients with diarrheas appearing after exposure of the gastro-intestinal region to ionizing radiation were given loperamide in the course of a study. A few days after administration of the loperamide, normalization of the stools took place, except in three cases. Simultaneous tenesmic gripes, some of the patients had also suffered from, disappeared completely, with the exception of two cases where, however, normalization of the stools was obtained by means of the loperamide therapy. Subjective side-effects did not occur. Also no alterations of the blood count, hematological features, liver function tests or urine have been observed.

摘要

在一项研究过程中,45名胃肠道接受电离辐射后出现腹泻的患者服用了洛哌丁胺。服用洛哌丁胺几天后,除3例患者外,大便恢复正常。一些患者同时出现的里急后重性绞痛也完全消失,只有2例除外,不过这2例患者通过洛哌丁胺治疗后大便恢复了正常。未出现主观副作用。血液计数、血液学特征、肝功能检查或尿液也未观察到变化。

相似文献

1
[Studies using loperamide in patients with diarrhea following telecobalt irradiation of malignant abdominal tumors (author's transl)].[使用洛哌丁胺治疗恶性腹部肿瘤钴远距离照射后腹泻患者的研究(作者译)]
Strahlentherapie. 1978 Jan;154(1):11-5.
2
Loperamide in patients with radiotherapy-induced diarrhoea.洛哌丁胺用于放疗引起腹泻的患者。
Arzneimittelforschung. 1978;28(5):864-6.
3
Loperamide: a new antidiarrheal agent in the treatment of chronic diarrhea.洛哌丁胺:一种治疗慢性腹泻的新型止泻药。
Gastroenterology. 1976 Jun;70(6):1026-9.
4
[Loperamide in acute diarrhea (author's transl)].洛哌丁胺治疗急性腹泻(作者译)
Rev Med Chil. 1977 Mar;105(3):174-5.
5
A double blind crossover comparison of loperamide with diphenoxylate in the symptomatic treatment of chronic diarrhea.洛哌丁胺与地芬诺酯对症治疗慢性腹泻的双盲交叉比较。
Gastroenterology. 1976 Jun;70(6):1030-4.
6
[Clinical results with loperamide in the treatment of chronic diarrhoea of varied aetiology (author's transl)].
Wien Klin Wochenschr. 1982 Mar 19;94(6):148-50.
7
[On radiogenic peripheral neuropathies following telecobalt irradiation in the abdominal cavity (author's transl)].
Radiobiol Radiother (Berl). 1974;15(4):459-64.
8
Loperamide in chronic diarrhea and after ileostomy: a placebo-controlled double-blind cross-over study.洛哌丁胺治疗慢性腹泻及回肠造口术后腹泻:一项安慰剂对照双盲交叉研究。
Arch Chir Neerl. 1976;28(1):13-20.
9
[Clinical analysis of acute intestinal radiation reaction following x-ray, radium and telecobalt irradiation].[X射线、镭及远距离钴照射后急性肠道放射反应的临床分析]
Strahlentherapie. 1966 Apr;129(4):512-9.
10
Loperamide, a new antidiarrheal agent in the treatment of chronic diarrhea.洛哌丁胺,一种用于治疗慢性腹泻的新型止泻药。
Schweiz Med Wochenschr. 1978 Jul 15;108(28):1080-1.

引用本文的文献

1
Gastrointestinal function in chronic radiation enteritis--effects of loperamide-N-oxide.慢性放射性肠炎的胃肠功能——洛哌丁胺氮氧化物的作用
Gut. 1993 Apr;34(4):476-82. doi: 10.1136/gut.34.4.476.