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Inhibition of phosphoribosylpyrophosphate synthesis in human fibroblasts by 6-methylthioinosinate.

作者信息

Yen R C, Raivio K O, Becker M A

出版信息

J Biol Chem. 1981 Feb 25;256(4):1839-45.

PMID:6257688
Abstract
摘要

相似文献

1
Inhibition of phosphoribosylpyrophosphate synthesis in human fibroblasts by 6-methylthioinosinate.6-甲硫基肌苷酸对人成纤维细胞中磷酸核糖焦磷酸合成的抑制作用。
J Biol Chem. 1981 Feb 25;256(4):1839-45.
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Methylmercaptopurine ribonucleoside toxicity in human fibroblasts: inhibition of phosphoribosylpyrophosphate synthetase as well as amidophosphoribosyltransferase.甲基巯基嘌呤核糖核苷对人成纤维细胞的毒性作用:对磷酸核糖焦磷酸合成酶及氨基磷酸核糖转移酶的抑制作用
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Inherited phosphoribosylpyrophosphate synthetase superactivity due to aberrant inhibitor and activator responsiveness.
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Transfer of resistance to selective conditions from fibroblasts with mutant feedback-resistant phosphoribosylpyrophosphate synthetase to normal cells. A form of metabolic cooperation.
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Increased phosphoribosylpyrophosphate synthetase activity in fibroblasts of hypoxanthine-guanine phosphoribosyl transferase deficient patients.次黄嘌呤 - 鸟嘌呤磷酸核糖转移酶缺乏患者成纤维细胞中磷酸核糖焦磷酸合成酶活性增加。
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Small elevations of glucose concentration redirect and amplify the synthesis of guanosine 5'-triphosphate in rat islets.葡萄糖浓度的小幅升高会改变并增强大鼠胰岛中三磷酸鸟苷的合成。
J Clin Invest. 1993 Aug;92(2):872-82. doi: 10.1172/JCI116662.
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Selective expression of phosphoribosylpyrophosphate synthetase superactivity in human lymphoblast lines.
磷酸核糖焦磷酸合成酶超活性在人淋巴母细胞系中的选择性表达。
J Clin Invest. 1985 Oct;76(4):1657-64. doi: 10.1172/JCI112151.