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尼日利亚的牛心水病。II. 从活体和死亡动物中分离反刍兽考德里氏体以及接种途径的重要性。

Heartwater in Nigeria. II. The isolation of Cowdria ruminantium from live and dead animals and the importance of routes of inoculation.

作者信息

Ilemobade A A, Blotkamp C

出版信息

Trop Anim Health Prod. 1978 Feb;10(1):39-44. doi: 10.1007/BF02235302.

DOI:10.1007/BF02235302
PMID:625798
Abstract

A study was carried out to determine which materials from animals dying or dead of heartwater could initiate the disease in susceptible goats, using the intravenous and subcutaneous routes. C. ruminantium was consistently isolated by intravenous injection of the whole blood or of lung macrophages and by subcutaneous injection of brain homogenate. In animals dead of heartwater, it appeared that isolation of the organism was achieved only when extensive post-mortem autolysis had not supervened. Experiments with blood fractions showed that leucocytic and plasma fractions of infective blood transmitted heartwater; the erythrocytic fraction consistently failed to induce an infection.

摘要

开展了一项研究,以确定来自动物因心水病死亡或濒死的哪些材料可通过静脉内和皮下途径在易感山羊中引发该病。通过静脉注射全血或肺巨噬细胞以及皮下注射脑匀浆,始终能分离到反刍兽考德里氏体。在因心水病死亡的动物中,似乎只有在死后未发生广泛自溶的情况下才能分离到该病原体。血液组分实验表明,感染性血液的白细胞和血浆组分可传播心水病;红细胞组分始终未能引发感染。

相似文献

1
Heartwater in Nigeria. II. The isolation of Cowdria ruminantium from live and dead animals and the importance of routes of inoculation.尼日利亚的牛心水病。II. 从活体和死亡动物中分离反刍兽考德里氏体以及接种途径的重要性。
Trop Anim Health Prod. 1978 Feb;10(1):39-44. doi: 10.1007/BF02235302.
2
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Isolation and transmission of Cowdria ruminantium (causal agent of heartwater disease) in Blue Nile Province, Sudan.牛心水病病原体——反刍动物考德里氏体在苏丹青尼罗省的分离与传播
Vet Res Commun. 1984 May;8(2):141-5. doi: 10.1007/BF02214705.
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The persistence of Cowdria ruminantium in the blood of recovered animals.反刍动物无形体在康复动物血液中的持续存在。
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Diagnosis of heartwater at post-mortem in ruminants and the confirmation of Cowdria ruminantium in mice.反刍动物死后心脏积水的诊断及小鼠中反刍动物考德里氏体的确认。
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引用本文的文献

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Tick-, Flea-, and Louse-Borne Diseases of Public Health and Veterinary Significance in Nigeria.尼日利亚具有公共卫生和兽医意义的蜱传、蚤传和虱传疾病。
Trop Med Infect Dis. 2018 Jan 3;3(1):3. doi: 10.3390/tropicalmed3010003.
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Identification of Cowdria ruminantium antigens that stimulate proliferation of lymphocytes from cattle immunized by infection and treatment or with inactivated organisms.鉴定通过感染与治疗或用灭活病原体免疫的牛的淋巴细胞增殖所刺激的反刍兽埃立克体抗原。
Infect Immun. 2000 Feb;68(2):603-14. doi: 10.1128/IAI.68.2.603-614.2000.
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Heartwater: cross-immunity studies with strains of Cowdria ruminantium isolated in West and South Africa.

本文引用的文献

1
STUDIES ON THE ETIOLOGY OF HEARTWATER : III. THE MULTIPLICATION OF RICKETTSIA RUMINANTIUM WITHIN THE ENDOTHELIAL CELLS OF INFECTED ANIMALS AND THEIR DISCHARGE INTO THE CIRCULATION.关于心水病病因的研究:III. 在感染动物的内皮细胞内繁殖的绵羊里奇氏体及其进入循环系统的排出。
J Exp Med. 1926 Nov 30;44(6):803-14. doi: 10.1084/jem.44.6.803.
2
Studies on pulmonary alveolar macrophages from the normal rabbit: a technique to procure them in a high state of purity.对正常兔肺泡巨噬细胞的研究:一种获取高纯度肺泡巨噬细胞的技术。
J Immunol. 1961 Feb;86:128-32.
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[Studies on cowdriosis in Madagascar. I].
心水病:对在西非和南非分离出的反刍兽考德里氏体菌株进行的交叉免疫研究。
Trop Anim Health Prod. 1981 Aug;13(3):160-4. doi: 10.1007/BF02237914.
[马达加斯加牛巴贝斯虫病研究。I]
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4
Pathogenesis of heartwater. I. Cowdria ruminantium in the lymph nodes of domestic ruminants.心水病的发病机制。I. 反刍动物淋巴结中的反刍兽考德里氏体。
Onderstepoort J Vet Res. 1970 Jun;37(2):89-95.
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A method for separation of bovine blood leukocytes for in vitro studies.一种用于体外研究的牛血白细胞分离方法。
Am J Vet Res. 1975 Aug;36(08):1091-4.
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Heartwater in Nigeria. I. The susceptibility of different local breeds and species of domestic ruminants to heartwater.
Trop Anim Health Prod. 1977 Aug;9(3):177-80. doi: 10.1007/BF02240335.
7
Electron microscopy of Cowdria ruminantium infected reticulo-endothelial cells of the mammalian host.
Onderstepoort J Vet Res. 1975 Mar;42(1):1-13.