Cairns J
Nature. 1981 Jan 29;289(5796):353-7. doi: 10.1038/289353a0.
The limited evidence available suggests that most human cancers are not caused by conventional mutagens but are more likely to be the result of genetic transpositions. Although the molecular biology of transposition is starting to be understood, the external factors that influence its frequency have not yet been studied in any detail.
现有有限的证据表明,大多数人类癌症并非由传统诱变剂引起,而更有可能是基因转座的结果。尽管转座的分子生物学开始为人所了解,但影响其频率的外部因素尚未得到详细研究。