Levchenko K P, Shchetinina E G
Ukr Biokhim Zh (1978). 1978 Jan-Feb;50(1):95-7.
Control of 25 sportsmen-wrestlers determined that accelerated loss in weight leads to a significant increase of ketone bodies evacuation with urine. The loss in weight for a 10-11 days period before a competition results in a less pronounced hyperketonuria. In experiment on rats it is shown that 48 and 98 hour hyperthermia and dehydration lead to the inhibition of the glucose-6-phosphate dehydrogenase activity in the liver. The mentioned permits supposing that under indicated conditions the inhibition of fat acid synthesis caused by NADPH2 and an increase of ketone bodies and cholesterol synthesis are observed.
对25名男子摔跤运动员的控制研究表明，体重的快速下降会导致尿中酮体排泄量显著增加。比赛前10 - 11天的体重减轻导致的高酮尿症不太明显。在对大鼠的实验中发现，48小时和98小时的高温及脱水会导致肝脏中葡萄糖-6-磷酸脱氢酶活性受到抑制。上述情况表明，在所示条件下会观察到由还原型辅酶II（NADPH2）引起的脂肪酸合成受抑制以及酮体和胆固醇合成增加。
