Zakharov N D, Kravtsov A N, Orlov I V
Zh Vyssh Nerv Deiat Im I P Pavlova. 1980 Nov-Dec;30(6):1279-83.
In experiments on unanesthetized non-immobilized rabbits, unit responses in the cortex and thalamus to the cyclic 3',5'-adenosine monophosphate (cAMPh) were studied by means of microionophoresis. It was shown that cAMPh changes the pattern of background unit activity, increasing or decreasing the discharge frequency. cAMPh changes unit responses both to acetylcholine and noradrenaline. These data permit, to assume that cAMPh participates both in adrenergic and in acetylocholinergic mechanisms of excitation processing in brain neurones.
在对未麻醉、未固定的兔子进行的实验中，通过微离子电泳法研究了大脑皮层和丘脑对环磷腺苷（cAMPh）的单位反应。结果表明，cAMPh改变了背景单位活动的模式，增加或降低了放电频率。cAMPh改变了单位对乙酰胆碱和去甲肾上腺素的反应。这些数据使我们可以假设，cAMPh参与了脑神经元兴奋过程中的肾上腺素能和乙酰胆碱能机制。
