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[粪肠球菌提取物对单纯疱疹病毒的体内和体外活性]

[In vivo and in vitro activity of Streptococcus faecium extract on Herpes simplex virus].

作者信息

Bonina L, Focà A, Merendino R

出版信息

Boll Soc Ital Biol Sper. 1980 Dec 15;56(23):2460-6.

PMID:6258615
Abstract

The effects of substance or substance extracted from Str. faecium SF 68 on HSV-1 are evaluated. The "in vivo" assay show that bacterial extract introduced i.p. in mice simultaneously with HSV-1 brought about 100% of survival, but bacterial extract after virus challenge brought about complete mortality of mice. "In vitro" assays show that bacterial extract reduce significantly PFU number. It seemed that Str. faecium extract affected the virus at the stage of adsorption on the host cells.

摘要

评估了屎肠球菌SF 68中的物质或提取物对单纯疱疹病毒1型(HSV - 1)的影响。“体内”试验表明,在给小鼠腹腔注射HSV - 1的同时注射细菌提取物,小鼠的存活率为100%,但在病毒攻击后注射细菌提取物则导致小鼠全部死亡。“体外”试验表明,细菌提取物显著降低了空斑形成单位(PFU)数量。似乎屎肠球菌提取物在病毒吸附于宿主细胞的阶段对病毒产生了影响。

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