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超氧自由基、过氧化氢、单线态氧和羟基自由基清除剂对牛精囊微粒体中花生四烯酸生成丙二醛的影响。

Effects of scavengers of superoxide radicals, hydrogen peroxide, singlet oxygen and hydroxyl radicals on malondialdehyde generation from arachidonic acid by bovine seminal vesicle microsomes.

作者信息

de Vries J, Verboom C N

出版信息

Experientia. 1980 Dec 15;36(12):1339-40. doi: 10.1007/BF01960084.

DOI:10.1007/BF01960084
PMID:6258964
Abstract

Superoxide dismutase, catalase and sodium formate did not inhibit the formation of malondialdehyde (MDA) from arachidonic acid, suggesting that O2-., H2O2 and OH. are not involved in the enzymatical oxidation of arachidonic acid. Sodium azide was found to be an inhibitor of MDA production.

摘要

超氧化物歧化酶、过氧化氢酶和甲酸钠并未抑制花生四烯酸生成丙二醛（MDA），这表明超氧阴离子、过氧化氢和羟自由基不参与花生四烯酸的酶促氧化过程。已发现叠氮化钠是丙二醛生成的抑制剂。

相似文献

1
Effects of scavengers of superoxide radicals, hydrogen peroxide, singlet oxygen and hydroxyl radicals on malondialdehyde generation from arachidonic acid by bovine seminal vesicle microsomes.超氧自由基、过氧化氢、单线态氧和羟基自由基清除剂对牛精囊微粒体中花生四烯酸生成丙二醛的影响。
Experientia. 1980 Dec 15;36(12):1339-40. doi: 10.1007/BF01960084.
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Effect of oxygen-derived free radicals and oxidants on the degradation in vitro of membrane phospholipids.氧衍生自由基和氧化剂对膜磷脂体外降解的影响。
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[Chemical and biochemical studies on reactivities, formations and toxicities of reactive oxygen species].
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Hydroxyl radical production from hydrogen peroxide and enzymatically generated paraquat radicals: catalytic requirements and oxygen dependence.过氧化氢产生的羟基自由基和酶促生成的百草枯自由基：催化要求和氧依赖性。
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Quantitative determination of prostaglandins and malondialdehyde formed by the arachidonate oxygenase (prostaglandin synthetase) system of bovine seminal vesicle.牛精囊花生四烯酸加氧酶（前列腺素合成酶）系统生成的前列腺素和丙二醛的定量测定。
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A remarkable deuterium effect on the rate of photosensitized oxidation of alcohol dehydrogenase and trypsin.氘对乙醇脱氢酶和胰蛋白酶光敏氧化速率有显著影响。
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Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent.生物防御机制。白细胞产生超氧化物，一种潜在的杀菌剂。
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