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腹膜后淋巴结清扫术的并发症。

Complications of retroperitoneal lymph node dissection.

作者信息

Donohue J P, Rowland R G

出版信息

J Urol. 1981 Mar;125(3):338-40. doi: 10.1016/s0022-5347(17)55029-6.

DOI:10.1016/s0022-5347(17)55029-6
PMID:6259378
Abstract

We reviewed the surgical morbidity in 235 patients who underwent retroperitoneal dissection for testis cancer. Of these patients 95 had stage I, 91 had stage II and 49 had stage III disease, and underwent a secondary or primary cytoreductive operation. In the early postoperative period there were 19 major complications in 13 patients (5.5 per cent) and 19 minor complications in 15 patients (6 per cent). There also were 3 late postoperative complications, 2 of which required re-hospitalization. Therefore, the over-all rate of 38 early major and minor complications in 28 patients (11.9 per cent) compares favorably to other reports. These complications generally are treated easily an successfully. However, there is a striking increase in the incidence of operative difficulties and postoperative complications in patients with advanced disease (stage III). Of 49 such patients there were 13 complications. One patient had multiple complications. Also, all patients who had an extensive primary cytoreductive operation suffered either intraoperative or postoperative complications. It is concluded that the complication rate is related directly to the extent of the disease. Factors contributing to this rate are increased operative time, added technical demands, diminished reserve and nutritional status of these patients, and the effects of prior chemotherapy. Therefore, a new population is emerging in cases of testis cancer, namely patients with extensive disease who have had prolonged intensive chemotherapy that alters the pulmonary, hematologic an nutritional status. Specific difficulties are noted and suggestions for management are reviewed.

摘要

我们回顾了235例因睾丸癌接受腹膜后淋巴结清扫术患者的手术并发症情况。这些患者中,95例为Ⅰ期,91例为Ⅱ期,49例为Ⅲ期疾病,并接受了二次或初次细胞减灭术。术后早期,13例患者出现19例严重并发症(5.5%),15例患者出现19例轻微并发症(6%)。术后还有3例晚期并发症,其中2例需要再次住院。因此,28例患者中38例早期严重和轻微并发症的总体发生率(11.9%)优于其他报告。这些并发症通常易于治疗且成功率高。然而,晚期疾病(Ⅲ期)患者的手术难度和术后并发症发生率显著增加。49例此类患者中有13例出现并发症。1例患者出现多种并发症。此外,所有接受广泛初次细胞减灭术的患者均出现术中或术后并发症。结论是并发症发生率与疾病范围直接相关。导致该发生率的因素包括手术时间延长、技术要求增加、这些患者的储备和营养状况下降以及先前化疗的影响。因此,睾丸癌病例中出现了一类新的人群,即患有广泛疾病且接受了长期强化化疗从而改变了肺部、血液学和营养状况患者。文中指出了具体困难并回顾了管理建议。

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