爱泼斯坦-巴尔病毒DNA：对人胎盘细胞的感染性。
Epstein-Barr viral DNA: infectivity for human placental cells.
作者信息
Miller G, Grogan E, Heston L, Robinson J, Smith D
出版信息
Science. 1981 Apr 24;212(4493):452-5. doi: 10.1126/science.6259735.
Purified DNA of Epstein-Barr virus (EBV) is regularly infectious by means of the "calcium" method of transfection. Cultured human placental cells exposed to EBV DNA of two transforming strains, FF41 and B95, produce virus that is capable of converting normal B lymphocytes into established cell lines. After treatment with EBV (FF41) DNA and EBV (HR-1) DNA the placental cells display antigens associated with the productive viral cycle. The placental cells have not developed foci or other signs of morphologic transformation.
通过“钙”转染法，爱泼斯坦 - 巴尔病毒（EBV）的纯化DNA具有常规传染性。暴露于两种转化株FF41和B95的EBV DNA的培养人胎盘细胞产生的病毒能够将正常B淋巴细胞转化为已建立的细胞系。在用EBV（FF41）DNA和EBV（HR - 1）DNA处理后，胎盘细胞显示出与活跃病毒周期相关的抗原。胎盘细胞未形成集落或其他形态转化迹象。
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